Tatalaksana Komprehensif Preeklampsia Berat Dengan Diabetes Melitus Gestasional Pada Kehamilan Aterm Usia Maternal Lanjut : Laporan Kasus

Authors

  • Eny Rahmawati Universitas Tarumanagara
  • Ernawati Ernawati Universitas Tarumanagara
  • Rabiah Adawiyah Universitas Tarumanagara

DOI:

https://doi.org/10.31004/koloni.v5i3.1151

Keywords:

Severe Preeclampsia, Gestational Diabetes Mellitus, Multiparity, Advanced Maternal Age, Caesarean Section

Abstract

Severe preeclampsia (PE) and gestational diabetes mellitus (GDM) are pregnancy complications that contribute significantly to maternal and perinatal morbidity and mortality . Both conditions increase the risk of endothelial dysfunction, uteroplacental insufficiency, fetal growth restriction, and labor complications. Early identification and appropriate management are crucial to prevent adverse outcomes for both mother and fetus. A woman presented with abdominal tenderness, accompanied by severe dizziness, the patient complained of swollen feet and dizziness since 22 weeks of pregnancy. The patient had a history of GDM diagnosed at 11 weeks of gestation (initial FBS 241 mg/dL) and a history of uncontrolled hypertension. Physical examination revealed a blood pressure of 164/108 mmHg and tachycardia (119 beats/minute). Supporting examinations confirmed hyperglycemia (RBG 220 mg/dL), proteinuria 3+ and glucosuria 2+. Ultrasonography (USG) revealed a single, live intrauterine fetus with an estimated fetal weight of 3397 grams. The patient was given initial therapy consisting of lung maturation with dexamethasone, seizure prophylaxis with magnesium sulfate, and nifedipine as an antihypertensive. Management of DMG includes nutritional therapy, and serial blood glucose monitoring. Immediate termination of pregnancy was performed via Caesarean section (CS) integrated with established contraception through the Method of Operating on Women (MOW) due to multiparity and medical risk Postoperative medical monitoring demonstrated good clinical recovery and stable hemodynamics until discharge. This case report aims to evaluate the clinical challenges and management of an elderly multiparous patient with severe preeclampsia and gestational diabetes.

References

American College of Obstetricians and Gynecologists. (2020a). Gestational Hypertension and Preeclampsia. The American College of Obstetricians and Gynecologists, 135(6).

American College of Obstetricians and Gynecologists. (2020b). Gestational Hypertension and Preeclampsia: ACOG Practice Bulletin No. 222. Obstetrics & Gynecology, 135(6), 237–260.

American Diabetes Association. (2023). Diagnosis and Classification of Diabetes: Standards of Care in Diabetes—2024. American Diabetes Association, 47, 20–42.

American Diabetes Association. (2026). Management of Diabetes in Pregnancy: Standards of Care in Diabetes. Diabetes Care, 49(1).

Aziz, F., Khan, M., & Moiz, A. (2024). Gestational diabetes mellitus, hypertension, and dyslipidemia as the risk factors of preeclampsia. Scientific Reports.

Barrell, A., & Sterruzzi-Perri, A. (2025). The Impact of Preeclampsia and Gestational Diabetes on Future Maternal Cardiometabolic Health. Acta Physiologica.

Budayasa, A., Afiatin, Kuncoro, A., Juli, C., & Hustrini, N. (2025). Panduan Penatalaksanaan Hipertensi pada Periode Peripartum (N. Hustrini, Ed.). Indonesian Society of Hypertension (InaSH) .

Countouris, M., Cohen, J., Harrington, C., & Mahmoud, Z. (2025). Hypertension in Pregnancy and Postpartum: Current Standards and Opportunities to Improve Care. AHA,

(7). https://doi.org/10.1161/CIRCULATIONAHA.124.073302

Elgazzaz, M., Maher, J., Woodham, P., & Faulkner, J. (2024). Implications of pregnancy on cardiometabolic disease risk: preeclampsia and gestational diabetes. American Journal of Physiology , 327(3).

International Society of Ultrasound in Obstetrics and Gynecology. (2023). ISUOG Practice Guidelines: role of ultrasound in hypertensive disorders of pregnancy. Ultrasound Obstet Gynecol.

Melesse, M., Badi, M., Aynalem, G., & Aynalem, B. (2025). Maternal outcomes of severe preeclampsia and eclampsia and associated factors among women admitted at referral hospitals of amhara regional state, institutional-based cross-sectional study, North-West Ethiopia. Frontiers in Women’s Health .

Perkumpulan Endokrinologi Indonesia. (2021). Pedoman Diagnosis dan Penatalaksanaan HIperglikemia dalam Kehamilan. PB PERKENI.

Sparic, R., Tinelli, A., & Stojkovic, M. (2024). Advanced maternal age (AMA) and pregnancy: a feasible but problematic event. Gynecology and Obstetrics , 310, 1365–1376.

Tanner, M., Davey, M., Rolnik, D., & Mol, B. (2022). The evolution of the diagnostic criteria of preeclampsia-eclampsia. American Journal of Obstetrics & Gynecology.

The American College of Obstetricians and Gynecologist. (2022). Pregnancy at Age 35 years or Older . Obstetrics & Gynecology, 140(2).

Yang, Y., & Wu, N. (2022). Gestational Diabetes Mellitus and Preeclampsia: Correlation and Influencing Factors. Frontiers in Cardiovascular Medicine .

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Published

23-08-2026

How to Cite

Rahmawati, E., Ernawati, E., & Adawiyah, R. (2026). Tatalaksana Komprehensif Preeklampsia Berat Dengan Diabetes Melitus Gestasional Pada Kehamilan Aterm Usia Maternal Lanjut : Laporan Kasus. KOLONI, 5(3), 2222–2232. https://doi.org/10.31004/koloni.v5i3.1151