Peranan T1-Weighted Post-Contrast dan Dynamic Susceptibility Contrast (DSC) Perfusion pada Pemeriksaan MRI Brain Pasien dengan Indikasi Klinis Epilepsi di Rumah Sakit Umum Pusat Surabaya

Putu Amanda Prasaka Putri; Ni Putu Rita Jeniyanthi; Nur Salsabila Sandy

doi:10.31004/koloni.v5i3.1402

Authors

Putu Amanda Prasaka Putri AKTEK Radiodiagnostik dan Radioterapi Bali
Ni Putu Rita Jeniyanthi AKTEK Radiodiagnostik dan Radioterapi Bali
Nur Salsabila Sandy Rumah Sakit Umum Pusat Surabaya

DOI:

https://doi.org/10.31004/koloni.v5i3.1402

Keywords:

epilepsy, brain MRI, T1-weighted post-contrast, DSC perfusion, hippocampus

Abstract

Epilepsy is a neurological disorder characterized by recurrent seizures caused by abnormal electrical activity in the brain and may be associated with structural or functional abnormalities. Magnetic resonance imaging (MRI) plays an important role in identifying the underlying causes of epilepsy and determining the need for additional imaging techniques. This study aimed to describe the role of T1-weighted post-contrast and Dynamic Susceptibility Contrast (DSC) perfusion in brain MRI examinations of patients with clinical indications of epilepsy at RSUP Surabaya. This study used a qualitative descriptive method with a multiple case study design involving three patients who underwent brain MRI examinations using a 1.5 Tesla Philips MRI scanner. Data were collected through image observation, examination documentation, radiology reports, and interviews with two radiographers and one radiologist. The results showed that T1-weighted post-contrast contributed to the evaluation of enhancement characteristics, particularly in a patient with a right temporal mass showing strong enhancement. In suspected mesial temporal sclerosis, the main findings were obtained from structural sequences, showing bilateral hippocampal FLAIR hyperintensity with right hippocampal atrophy without abnormal enhancement. DSC perfusion provided additional information regarding tissue perfusion, showing perfusion differences between the lesion and contralateral tissue in the mass case. This study concludes that T1-weighted post-contrast and DSC perfusion have complementary roles and can be selectively applied according to MRI findings and clinical needs in epilepsy patients.

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