Hubungan Riwayat Neuropati Dengan Kejadian Ulkus Diabetikum Pada Pasien Diabetes Melitus Tipe 2 Di RSUD Meuraxa Banda Aceh
DOI:
https://doi.org/10.31004/koloni.v5i3.1321Keywords:
type 2 diabetes mellitus, diabetic neuropathy, diabetic ulcers. ”Abstract
Type 2 diabetes mellitus (T2DM) is a long-term metabolic disorder that may lead to diabetic ulcers. Diabetic neuropathy is an important predisposing factor because diminished protective sensation in the lower limbs can make patients unaware of minor trauma or wounds. Without early recognition and treatment, these injuries may progress to more severe lesions. Objective: To examine the association between a history of neuropathy and the occurrence of diabetic ulcers among patients with T2DM at Meuraxa Regional General Hospital, Banda Aceh. Methods: An analytic observational study with a cross-sectional design was conducted. All 36 eligible respondents were included using total sampling. Neuropathy data were collected with the Michigan Neuropathy Screening Instrument (MNSI), and the association was analyzed using the Fisher-Freeman-Halton Exact Test. Most respondents had a history of neuropathy, and this history was significantly associated with diabetic ulcer occurrence, with p=0.010 (p<0.05). Ulcers tended to be more severe among respondents with neuropathy than among those without neuropathy. The findings indicate an association between neuropathy history and diabetic ulcers in patients with T2DM treated at Meuraxa Regional General Hospital, Banda Aceh. Early identification and appropriate management of diabetic neuropathy, together with foot-care education, routine foot assessment, and adequate blood glucose control, are important to reduce ulcer formation and subsequent complications.
References
Primadani AF, Safitri DNP. Proses Penyembuhan Luka Kaki Diabetik Dengan Perawatan Luka Metode Moist Wound Healing. Ners Muda. 2021;2(1):9. https://www.academia.edu/download/107509393/pdf.pdf
Kebede SA, Tusa BS, Weldesenbet AB, Tessema ZT, Ayele TA. Time to diabetic neuropathy and its predictors among newly diagnosed type 2 diabetes mellitus patients in Northwest Ethiopia. Egypt J Neurol Psychiatry Neurosurg. 2021;57(1). https://link.springer.com/article/10.1186/s41983-021-00402-4
Kesehatan BKP. Survei Kesehatan Indonesia 2023. https://badankebijakan.kemkes.go.id/
KesehatanBandaAcehP.ProfilKesehatan.;2020 https://dinkes.bandaacehkota.go.id/wp
Utami Cahyaningtyas, Rini Werdiningsih. Analisis Faktor Lama Penyembuhan Kaki Diabetes/Ulkus Diabetikum Pada Pasien Dm Tipe 2. J Media Adm. 2022;7(1):28-39. https://jurnal2.untagsmg.ac.id/index.php/jma/article/view/61
Pfannkuche A, Alhajjar A, Ming A, Walter I, Piehler C, Mertens PR. Prevalence and risk factors of diabetic peripheral neuropathy in a diabetics cohort: Register initiative “diabetes and nerves.” Endocr Metab Sci. 2020;1(1-2). https://www.sciencedirect.com/science/article/pii/S2666396120300078
Alhuda, Sabil TM, Gaol LL, Keperawatan A, Iskandar K, Lhokseumawe M. Upaya Pencegahan Diabetes Mellitus Dengan Mengontrol Kadar Gula Darah Pada Masyarakat Silih Nara Aceh Tengah. Pabma J Pengabdi Masy Madani. 2024;1(1):34-39. https://journal.elfarazy.com/index.php/pabma/article/view/7
Care D, Suppl SS. 12. Foot Care : Standards of Medical Care in Diabetes
— 2022. Diabetes Care. 2022;45(January):185-194. https://healthy.arkansas.gov/wp-content/uploads/ADA_Classification_and_Diagnosis_of_Diabetes.pdf
Lestari, Zulkarnain, Sijid, Aisyah S. Diabetes Melitus: Review Etiologi, Patofisiologi, Gejala, Penyebab, Cara Pemeriksaan, Cara Pengobatan dan CaraPencegahan.U I N AlauddinMakassar.2021;1(2):237241 https://journal.uin-alauddin.ac.id/index.php/psb/article/view/24229
Soelistijo S. Pedoman Pengelolaan dan Pencegahan Diabetes Melitus Tipe 2 Dewasa di Indonesia 2021. Glob Initiat Asthma. Published online 2021:46. www.ginasthma.org. https://pbperkeni.or.id/wp-content/uploads/2021/11/22-10-21-Website-Pedoman-Pengelolaan-dan-Pencegahan-DMT2-Ebook.pdf
Araszkiewicz A, Bandurska-Stankiewicz E, Borys S, et al. 2021 Guidelines on the management of patients with diabetes. A position of Diabetes Poland Clin Diabetol.2021;10(1):1-113. https://journals.viamedica.pl/endokrynologia_polska/article/view/88685
Siddiq MS, Fahmi I, Aramico B. Faktor Resiko Kejadian Diabetes Melitus Pada Usia Produktif Di Wilayah Kerja Puskesmas Lampaseh Kecamatan Kuta Raja Kota Banda Aceh. J Kesehat Tambusai. 2023;4(3):94-102. https://journal.universitaspahlawan.ac.id/index.php/jkt/article/view/16472/13318
Silalahi LE, Prabawati D, Hastono SP. The effectiveness of self-care education on selfmanagement behavior in Diabetes Meillitus patients at the area of Puskesmas Sukapura Jakarta. Media Publ Promosi Kesehat Indonesia. 2021;4(1):15-22. https://www.jurnal.unismuhpalu.ac.id/index.php/MPPKI/article/view/1385
Aleidan FA, Ahmad BA, Alotaibi FA, et al. Prevalence and risk factors for diabetic peripheral neuropathy among saudi hospitalized diabetic patients: A nested casecontrol study. Int J Gen Med. 2020;13:881-889. https://www.tandfonline.com/doi/abs/10.2147/IJGM.S273807
Ariadi A, Mustiadji A, Alimurdianis. Ketoasidosis Diabetikum. Sci J. 2024;3(6):375-383. https://journal.scientic.id/index.php/sciena/article/view/174
Selano MK. diabetic foot ulcer and their surgical management. J Smart Keperawatan. 2021;8(2):129. https://pmc.ncbi.nlm.nih.gov/articles/PMC10689580/
Pamungkas RA, Usman AM, Chamroonsawasdi K. Clinical Features of Peripheral Neurophaty among Onset Type 2 Diabestes Mellitus: A Michigan Neuropathy Screening Instrument (MNSI) Approach. Indones Contemp Nurs J (ICON Journal). 2023;7(2):46-52. https://journal.unhas.ac.id/index.php/icon/article/view/21689
Mizukami H. Pathological evaluation of the pathogenesis of diabetes mellitus and diabetic peripheral neuropathy. Pathol Int. 2024;74(8):438- 453. https://onlinelibrary.wiley.com/doi/abs/10.1111/pin.13458
Juster-Switlyk K, Smith AG. Updates in diabetic peripheral neuropathy.F1000Research. 2016;5(0):1-7. https://pmc.ncbi.nlm.nih.gov/articles/PMC4847561/
Ogbeide OA, Okeleke SI, Okorie JC, et al. Evolving Trends in the Management of Diabetic Foot Ulcers: A Narrative Review. Cureus. 024;16(7). https://www.cureus.com/articles/269419-evolving-trends-in-the-management-of-diabetic-foot-ulcers-a-narrative-review.pdf
Muhammad Hafizh Izuddin Alzamani L, Rianta Yolanda Marbun M, Eka Purwanti M, Salsabilla R, Rahmah S. Ulkus Kronis: Mengenali Ulkus Dekubitus dan Ulkus Diabetikum. J Syntax Fusion . 2022;2(02):272-286. https://pdfs.semanticscholar.org/9fa6/a98a9fdd0a69a96431d7be4bf6301b11075c.pdf
Nisak R. The Occurrence and Classification of Diabetic Ulcers Among Diabetes Mellitus Patients Using Wagner-Ulcer Classification Tool. J Ilm Keperawatan. 2021;Vol.07:156-165. https://journal.stikespemkabjombang.ac.id/index.php/jikep/article/view/729
Waibel FWA, Uçkay I, Soldevila-Boixader L, Sydler C, Gariani K. Current knowledge of morbidities and direct costs related to diabetic foot disorders:aliterature review. Front Endocrinol (Lausanne). 2023;14(January):1-8. https://www.frontiersin.org/journals/endocrinology/articles/10.3389/fendo.2023.1323315/full
Fan Z, Huang J, Liu Y, et al. Multifactorial analysis of risk factors for foot ulcers in patients with neurovascular complications of diabetes. Front Endocrinol(Lausanne).2024;15(October):1-9. https://www.frontiersin.org/journals/endocrinology/articles/10.3389/fendo.2024.1399924/full
van Netten JJ, Raspovic A, Lavery LA, et al. Prevention of foot ulcers in persons with diabetes at risk of ulceration: A systematic review and meta- analysis. Diabetes Metabolik Res Rev. 2024;40(3). https://onlinelibrary.wiley.com/doi/abs/10.1002/dmrr.3652
Ana Nistiandani, Rondhianto R, Fakhrur Rozsy M. Overview of Motor Nerve Damage in People with Diabetes Mellitus. Nurs Heal Sci J. 2021;1(3):242-248. https://www.academia.edu/download/90220458/43.pdf
Anggreni, Dhonna, and S. Km. "Buku Ajar-Metodologi Penelitian Kesehatan." E-Book Penerbit STIKes Majapahit (2022). https://www.ejournal.stikesmajapahit.ac.id/index.php/EBook/article/download/806/812
Subhaktiyasa, Putu Gede. "Menentukan populasi dan sampel: Pendekatan metodologi penelitian kuantitatif dan kualitatif." Jurnal Ilmiah Profesi Pendidikan 9.4 (2024): 2721-2731. https://jipp.unram.ac.id/index.php/jipp/article/view/2657
Pangestika, H., Ekawati, D., & Murni, N. S. (2022). Faktor-faktor yang berhubungan dengan kejadian diabetes mellitus tipe 2. Jurnal’Aisyiyah Medika, 7(1), 27-31. https://scholar.google.co.id/citations?user=7UCBY1cAAAAJ&hl=id&oi=sra
rabowo, Dwi Yogo Budi; Deram, Muhammad Deram. Hubungan Pengetahuan dengan Perawatan Kaki Mandiri Pada Pasien Diabetes Melitus Tipe II. Global Nursing and Public Health, 2025, 1.1. https://scholar.google.co.id/citations?user=Ndlg4KMAAAAJ&hl=id&oi=sra
Chaidir, Andi Fahira, et al. "Karakteristik Penyandang Diabetes Melitus Tipe 2." Fakumi Medical Journal: Jurnal Mahasiswa Kedokteran 4.9 (2024): 613-619. https://scholar.google.co.id/citations?user=nW75_UsAAAAJ&hl=id&oi=sra
Wang C-S, Pai Y-W, Lin C-H, Lee I-T, Chen H-H and Chang M-H (2024) Diabetic peripheral neuropathy: age-stratified glycemic control. Front. Endocrinol. https://www.frontiersin.org/journals/endocrinology/articles/10.3389/fendo.2024.1377923/full
Anandhanarayanan A, Teh K, Goonoo M, et al. Diabetic Neuropathies. [Updated 2022 Mar 15]. In: Feingold KR, Adler RA, Ahmed SF, et al., editors. Endotext [Internet]. South Dartmouth (MA): MDText.com, Inc.; 2000 https://www.ncbi.nlm.nih.gov/books/NBK279175/
Salsabila, K., Kurniati, I., Wulan, A. J., & Wintoko, R. (2026). Hubungan Kadar HBA1C Dengan Derajat Ulkus Diabetik Menurut Klasifikasi MEGGITT-WAGNER Pada Pasien Diabetes Melitus Tipe 2 di RSUD DR. H. Abdul Moelek Bandar Lampung Periode Januari-Juli 2022. Medical Profession Journal of Lampung, 16(1), 35-41. http://www.journalofmedula.com/index.php/medula/article/view/1718
Sarwanto A, Nurrohmah A. Gambaran Pengetahuan Tentang Pencegahan Ulkus pada Penderita Diabetes Mellitus di Wilayah Kerja Puskesmas Grogol Kabupaten Sukoharjo. Journal of Golden Generation Health. 2025;2(1). https://ejournal.lppnusantara.com/index.php/JGGH/article/view/483
Nipa Y, Rifatunnisa, Paschalia YPM. Asuhan Keperawatan Ulkus Diabetes Melitus: Laporan Kasus. Kelimutu Nursing Journal. 2023;2(2). https://scholar.google.co.id/citations?user=Ot_-du8AAAAJ&hl=id&oi=sra
Nistiandani A, Hakam M, Sutawardana JH, Widayati N, Siswoyo, Kurniawan FA. Identifikasi Risiko Terjadinya Ulkus Diabetik Berbasis Diabetic Foot Screening pada Pasien DM Tipe 2. JI-KES (Jurnal Ilmu Kesehatan). 2023;6(2):162–170. https://journal.unhasa.ac.id/index.php/jikes/article/view/521
Rohmatulloh, Vanda Rizky, et al. "Hubungan usia dan jenis kelamin terhadap angka kejadian diabetes melitus tipe 2 berdasarkan 4 kriteria diagnosis di Poliklinik Penyakit Dalam RSUD Karsa Husada Kota Batu." Prepotif: Jurnal Kesehatan Masyarakat 8.1 (2024): 2528-2543. http://repository.uin-malang.ac.id/18897/
Downloads
Published
How to Cite
Issue
Section
License
Copyright (c) 2026 Zurriyani Zurriyani, Eva Mardalena, Sintia Purnama

This work is licensed under a Creative Commons Attribution-ShareAlike 4.0 International License.


