PROFIL SENYAWA EKSTRAK DAN FRAKSI BATANG BIDARA LAUT (Strychnosligustrina Blume) DENGAN METODE KLT DAN GCMS

Authors

  • Megawati Megawati Sekolah Tingggi Ilmu Farmasi Makassar
  • Khairuddin Khairuddin Sekolah Tinggi Ilmu Farmasi Makassar

DOI:

https://doi.org/10.31004/koloni.v2i1.436

Abstract

Bidara laut (Strychnos ligustrina Blume) is one of the plants belonging for longaniacea family. Empirically the people of Bima Dompu Bidara laut (Strychnos ligustrina Blume) are used to treat rheumatism, wounds and malaria. This research was conducted identify the profile of the stem Bidara laut compounds by Thin Layer Chromatography and GC-MS. Simplisia the stem Bidara laut extracted by reflux method using ethanol 96%. The results of this study obtained rendamen of 2.7%. Phytochemical screening shows extract containing alkaloids, flavonoids, saponins and tannins. Thin layer chromatography testing of the positive ethyl acetate fraction containing saponins and tannins, the positive n-hexan fraction containing flavonoids and saponins, the positive methanol fraction containing saponins. The results of identification using GC-MS obtained Sucrose, 3-O-Methyl-d-glucose, n-Hexadecanoicacid, Hexadecanoicacid, ethyl ester, Oleicacid, Hexadecanoicacid, 2-hydroxy-1 (hydroxymethyl) ethyl ester, 9-Octadecenoic acidacid (Z) -, 2-hydroxy-1-1 (hydroxymethyl) ethyl ester, and Stigmasterol. 

Keywords: Strycnos ligustrina Blume, Identification, Extract Fraction, Thin layer chromatography, GC-MS

 

References

Bero J, Frederich M, Leclerq JQ. 2009. “Antimalarial compounds isolated from plants used in traditional medicine”. JPP 61:1401-1433.

Gandjar, I. G. dan A. Rohman. 2007. “Kimia Analisis Farmasi”. Yogyakarta

Harborne, J.B. 1987. Metode Fitokimia: Penuntun Cara Modern Menganalisis Tumbuhan. Terbitan Kedua. Bandung: Penerbit ITB. Hal. 127.

Kristianti, A. N, N. S. Aminah, M. Tanjung, dan B. Kurniadi. 2008. “Buku Ajar Fitokimia. Surabaya: Jurusan Kimia Laboratorium Kimia Organik”. FMIPA Universitas Airlangga. P.47-48.

Marjoni, Riza. 2016. “Dasar-Dasar Fitokimia”. CV.Trans Info Media. Jakarta

Nogueira C, Lopes LMX. 2011. “ Antiplasmodial natural products. Molecules 16”. 2146-2190.

Saxena S, Pant N, Jain DC, Bhakuni RS. “Antimalarial agents from plant sources”. Current Sci 85(9):1314-1329.

Wijayakusuma, Hembing. 2005. “Atasi Kanker dengan Tanaman Obat”. Puspa Swara. Jakarta

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Published

31-03-2023

How to Cite

Megawati, M., & Khairuddin, K. (2023). PROFIL SENYAWA EKSTRAK DAN FRAKSI BATANG BIDARA LAUT (Strychnosligustrina Blume) DENGAN METODE KLT DAN GCMS. KOLONI, 2(1), 234–241. https://doi.org/10.31004/koloni.v2i1.436

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